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1

Covalent protein immobilization on glass surfaces: Application to alkaline phosphatase

Russell H. Taylor, Sylvie M. Fournier, Brigitte L. Simons, Harvey Kaplan, Mary Alice Hefford

Journal:

Journal of Biotechnology

Year:

2005

Language:

english

File:

PDF, 104 KB

english, 2005

2

Cytotoxic Doses of Ketoconazole Affect Expression of a Subset of Hepatic Genes

Casley, William L., Ogrodowczyk, Carolina, Larocque, Louise, Jaentschke, Bozena, LeBlanc-Westwood, Carole, Menzies, J. Allan, Whitehouse, Larry, Hefford, Mary Alice, Aubin, Rémy A., Thorn, Caroline F.

Journal:

Journal of Toxicology and Environmental Health

Year:

2007

Language:

english

File:

PDF, 891 KB

english, 2007

3

Glycation improves the thermostability of trypsin and chymotrypsin

Van Thong Pham, Erin Ewing, Harvey Kaplan, Christin Choma, Mary Alice Hefford

Journal:

Biotechnology and Bioengineering

Year:

2008

Language:

english

File:

PDF, 327 KB

english, 2008

4

A novel cross-linked RNase A dimer with enhanced enzymatic properties

Brigitte L. Simons, Harvey Kaplan, Sylvie M. Fournier, Terry Cyr, Mary Alice Hefford

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 690 KB

english, 2007

5

O-Linked Glycosylation Leads to Decreased Thermal Stability of Interferon Alpha 2b as Measured by Two Orthogonal Techniques

Michael James Wilson Johnston, Grant Frahm, Xuguang Li, Yves Durocher, Mary Alice Hefford

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 312 KB

english, 2011

6

Enhancement of essential amino acid contents in crops by genetic engineering and protein design

Marc Beauregard, Mary Alice Hefford

Journal:

Plant Biotechnology Journal

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

7

Introduction of potential helix-capping residues into an engineered helical protein

Matthew H. Parker, Mary Alice Hefford

Journal:

Biotechnology and Applied Biochemistry

Year:

1998

Language:

english

File:

PDF, 382 KB

english, 1998

8

Analysis of the sequence of a new cryptic plasmid, pRJF2, from a rumen bacterium of the genus Butyrivibrio: Comparison with other Butyrivibrio plasmids and application in the development of a cloning vector

Yasuo Kobayashi, Robert J. Forster, Mary Alice Hefford, Ronald M. Teather, Masaaki Wakita, Kunio Ohmiya, Sadao Hoshino

Journal:

FEMS Microbiology Letters

Year:

1995

Language:

english

File:

PDF, 612 KB

english, 1995

9

Use of the pH Memory Effect in Lyophilized Proteins to Achieve Preferential Methylation of α-Amino Groups

Helen T. Vakos, Harvey Kaplan, Bruce Black, Brian Dawson, Mary Alice Hefford

Journal:

The Protein Journal

Year:

2000

Language:

english

File:

PDF, 48 KB

english, 2000

10

In Vacuo Esterification of Carboxyl Groups in Lyophilized Proteins

Helen T. Vakos, Bruce Black, Brian Dawson, Mary Alice Hefford, Harvey Kaplan

Journal:

The Protein Journal

Year:

2001

Language:

english

File:

PDF, 194 KB

english, 2001

11

Covalent cross-linking of proteins without chemical reagents

Brigitte L. Simons, Mary C. King, Terry Cyr, Mary Alice Hefford, Harvey Kaplan

Journal:

Protein Science

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

12

Utility of standard pharmacopeial and nonpharmacopeial methods in distinguishing folded, unfolded, and process variant forms of interferon α-2

John K. Mark, Sophie Dionne, Terry D. Cyr, Sylvie Boucher, Michel Girard, Mary Alice Hefford

Journal:

Journal of Pharmaceutical Sciences

Year:

2012

Language:

english

File:

PDF, 460 KB

english, 2012

13

Thermal Stability: A Means to Assure Tertiary Structure in Therapeutic Proteins

Mike Cauchy, Sophie D'aoust, Brian Dawson, Harold Rode, Mary Alice Hefford

Journal:

Year:

2002

Language:

english

File:

PDF, 188 KB

english, 2002

14

Excipient exchange in the comparison of preparations of the same biologic made by different manufacturing processes: An exploratory study with recombinant human growth hormone (rhGH)

Mike Cauchy, Mary Alice Hefford

Journal:

Year:

2010

Language:

english

File:

PDF, 292 KB

english, 2010

15

Novel cross-linked enzyme–antibody conjugates for Western blot and ELISA

Brigitte Simons, Harvey Kaplan, Mary Alice Hefford

Journal:

Journal of Immunological Methods

Year:

2006

Language:

english

File:

PDF, 391 KB

english, 2006

16

Characterization of MB-1 : A dimeric helical protein with a compact core

Mary Alice Hefford, Claude Dupont, Jillian MacCallum, Matthew H. Parker, Marc Beauregard

Journal:

Year:

1999

Language:

english

File:

PDF, 650 KB

english, 1999

17

SARS coronavirus: Unusual lability of the nucleocapsid protein

John Mark, Xuguang Li, Terry Cyr, Sylvie Fournier, Bozena Jaentschke, Mary Alice Hefford

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 324 KB

english, 2008

18

Over-expression and refolding of MAP kinase phosphatase 3

John K. Mark, Sophie Smith, Mary Alice Hefford

Journal:

Protein Expression and Purification

Year:

2007

Language:

english

File:

PDF, 590 KB

english, 2007

19

Sequence of a lepidopteran toxin gene of bacillus thuringiensis subsp kurstaki NRD-12

Hefford, Mary Alice, Brousseau, Roland, Préfontaine, Gabrielle, Hanna, Zaher, Condie, Janet A, Lau, Peter C.K

Journal:

Journal of Biotechnology

Year:

1987

Language:

english

File:

PDF, 931 KB

english, 1987

20

Unusual chemical properties of N-terminal histidine residues of glucagon and vasoactive intestinal peptide

Hefford, Mary Alice, Evans, Robyn M., Oda, George, Kaplan, Harvey

Journal:

Year:

1985

Language:

english

File:

PDF, 962 KB

english, 1985

21

Engineering Nutritious Proteins

Hefford, Mary Alice

Journal:

Biotechnology and Genetic Engineering Reviews

Year:

1997

Language:

english

File:

PDF, 1.58 MB

english, 1997

22

Bipartite organization of the Bacillus subtilis endo-β-1,4-glucanase revealed by C-terminal mutations

Hefford, Mary Alice, Laderoute, Keith, Willick, Gordon E., Yaguchi, Makoto, Seligy, Verner L.

Journal:

Protein Engineering Design and Selection

Year:

1992

Language:

english

File:

PDF, 4.24 MB

english, 1992

23

Identification of N- and C-Terminal Residues Involved in MAP Kinase Phosphatase 3 (MKP3) Interdomain Binding and Auto-Inhibition

K. Mark, John, J.W. Johnston, Michael, Alice Hefford, Mary

Journal:

Protein & Peptide Letters

Year:

2010

Language:

english

File:

PDF, 198 KB

english, 2010